Focusing on Preinvasive Neoplasia
نویسندگان
چکیده
منابع مشابه
Leaders Pulmonary preinvasive neoplasia
Advances in molecular biology have increased our knowledge of the biology of preneoplastic lesions in the human lung. The recently published WHO lung tumour classification defines three separate lesions that are regarded as preinvasive neoplasia. These are (1) squamous dysplasia and carcinoma in situ (SD/CIS), (2) atypical adenomatous hyperplasia (AAH), and (3) diVuse idiopathic pulmonary neuro...
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The etiology and pathogenesis of human transitional cell carcinoma (TCC) remain unknown at the present time. While many carcinogens can induce bladder carcinoma in animal experimental studies, the only well-established carcinogens in human beings are tobacco smoke and arylamines.[1] Experimental studies in animals have demonstrated that invasive urothelial carcinoma is preceded by a sequence of...
متن کاملThe impact of human immunodeficiency virus infection on cervical preinvasive and invasive neoplasia in South Africa
OBJECTIVES Sub-Saharan Africa is at the epicentre of the human immunodeficiency virus (HIV) epidemic and has the highest incidence of invasive cervical cancer (ICC) in the world. Access to highly active antiretroviral treatment (HAART) in South Africa is still limited and provided only to nonpregnant women with a CD4+ T-cell count <200 μg/L. We evaluated the relative distribution of cervical pr...
متن کاملp16INK4A, CDC6, and MCM5: predictive biomarkers in cervical preinvasive neoplasia and cervical cancer.
AIM To analyse and compare expression patterns of three potential biomarkers-p16(INK4A), CDC6, and MCM5-and evaluate their use as predictive biomarkers in squamous and glandular cervical preinvasive neoplasia. METHODS Immunocytochemical analysis of p16(INK4A), MCM5, and CDC6 expression was performed on 20 normal, 38 cervical intraepithelial neoplasia 1 (CIN1), 33 CIN2, 46 CIN3, 10 squamous ce...
متن کاملResults of Two Years Expenience with Fluorescence Bronchoscopy in Detection of Preinvasive Bronchial Neoplasia
The aim of the study was to determine whether use of fluorescence bronchoscopy improves the detection of preinvasive neoplastic bronchial lesions. The data of all patients who underwent fluorescence bronchoscopy and in whom bronchial biopsies were taken, were analyzed. Most patients were at risk for preinvasive lesions. A total of 174 bronchoscopies were performed in 95 patients. Of the 681 rep...
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ژورنال
عنوان ژورنال: Archives of Pathology & Laboratory Medicine
سال: 2018
ISSN: 0003-9985,1543-2165
DOI: 10.5858/arpa.2017-0581-le